ALPHA-PURE XANTHONE
Pure xanthone extract from mangosteen peel with antimicrobial properties, inhibits collagen and bacteria production, fights free radicals, reduces inflammation and nourishes the skin to look youthful.
Alpha-Pure XANTHONE – Purified Mangosteen Xanthone for Advanced Wellness & Beauty
Alpha-Pure XANTHONE is a high-purity active ingredient derived from mangosteen peel (Garcinia mangostana), offering potent antioxidant, anti-aging, and antimicrobial properties for cutting-edge supplement and cosmetic formulations.
The Story Behind Mangosteen’s Healing Peel

Thailand’s cherished “queen of fruits,” the mangosteen, has long been prized not only for its delicious white flesh but also for the potent properties of its purple rind. In traditional Thai medicine, mangosteen peel was used as a natural remedy for healing wounds, reducing inflammation, and even as a skin treatment – valued for its astringent, antibacterial and skin-brightening effects. These ancestral insights laid the groundwork for modern science: researchers later discovered that mangosteen rind is rich in xanthones, a class of polyphenolic compounds responsible for many of the fruit’s medicinal qualities. The most abundant xanthone, alpha-mangostin, is a molecule now recognized for its powerful bioactivity. Alpha-Pure XANTHONE was born from the synergy of this traditional wisdom and state-of-the-art biotechnology. Developed by Zubb Biotech in Thailand, this ingredient harnesses the essence of mangosteen peel in its purest form, marrying a proud local heritage with world-class innovation. By concentrating the key actives of Garciniamangostana, Zubb Biotech enables health and beauty product developers to incorporate a legendary Asian botanical into novel formulations with confidence in its efficacy and authenticity.
Alpha-Pure XANTHONE by Zubb Biotech: Purity Meets Performance
Alpha-Pure XANTHONE is a purified mangosteen peel extract standardized for a high concentration of xanthones – particularly alpha-mangostin – without unnecessary fillers or additives. Presented as a fine, light-yellow powdered extract, it provides formulators with a potent and versatile ingredient that can be easily integrated into both nutraceutical and cosmetic products. The purification process yields a remarkably high potency extract compared to typical mangosteen powders, meaning smaller doses can deliver effective results. With its origin in 100% natural plant material, Alpha-Pure XANTHONE aligns with clean-label demands while delivering a robust dose of scientifically validated phytochemicals. Each batch is produced under stringent quality controls: Zubb Biotech ensures that every lot is rigorously tested for safety, purity, and potency, so manufacturers receive a consistent, reliable active ingredient for their product development needs. In summary, Alpha-Pure XANTHONE offers an efficient way to incorporate the health-boosting and cosmetic benefits of mangosteen into premium products, backed by Zubb Biotech’s technical expertise and commitment to excellence.
Proven Power: The Bioactive Benefits of Purified Xanthone
Alpha-Pure XANTHONE provides a spectrum of science-backed benefits for both wellness and personal care applications:
- Powerful Antioxidant: Xanthones from mangosteen neutralize free radicals and protect cells from oxidative damage. Studies show that these antioxidants can combat aging and chronic disease at the cellular level. By stabilizing harmful free radicals, Alpha-Pure XANTHONE helps preserve skin vitality and supports overall health.
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Anti-Inflammatory Activity: The extract’s active compounds have demonstrated significant anti-inflammatory effects, which soothe irritated skin and support the body’s response to inflammation. This makes it valuable in formulations aimed at calming redness or swelling, and in supplements for joint or metabolic health.
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Anti-Aging & Skin Revitalization: Alpha-Pure XANTHONE helps protect and rejuvenate skin through multiple mechanisms. Research indicates that mangosteen peel extract inhibits collagenase and elastase enzymes that break down skin collagen and elastin, as well as hyaluronidase that degrades hyaluronic acid. By safeguarding these structural and moisturizing elements, it helps maintain skin firmness, hydration, and elasticity. Additionally, xanthones (e.g. γ-mangostin) show anti-tyrosinase activity, which can inhibit melanin production for a brighter, more even complexion. Together, these actions make Alpha-Pure a powerful anti-aging ingredient to help reduce the appearance of wrinkles, fine lines, and age spots.
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Antimicrobial & Acne-Fighting: Mangosteen xanthones have natural antimicrobial properties effective against acne-causing bacteria. Alpha-Pure XANTHONE delivers this benefit in a concentrated form. Laboratory studies show alpha-mangostin can inhibit Propionibacterium acnes and Staphylococcus epidermidis at very low concentrations. In a clinical trial, a mangosteen peel extract gel led to a 47% reduction in acne lesions within 28 days, highlighting its potential for clearer skin. This antimicrobial and anti-inflammatory one-two punch makes Alpha-Pure ideal for anti-acne skincare products and other applications requiring plant-based antimicrobial efficacy.
Each benefit is supported by scientific evidence or traditional use, underscoring Alpha-Pure XANTHONE’s value as a multi-functional ingredient. By incorporating this extract, product developers can confidently add claims of antioxidant potency, anti-aging effects, improved skin health, and more – all backed by credible research.
Scientific Sophistication: Precision Extraction for Potency & Purity
Alpha-Pure XANTHONE is the result of Zubb Biotech’s cutting-edge innovation in natural product extraction and purification. The development team employed advanced techniques to isolate xanthones from mangosteen pericarp at high purity, ensuring maximum bioactive content in every batch. This process, refined through collaboration with leading research institutions like Kasetsart University, delivers an ingredient with robust efficacy while remaining naturally derived. Unlike crude fruit powders that can vary in composition, Alpha-Pure XANTHONE is processed to remove inactive components and concentrate the most beneficial molecules. The extraction technology preserves the integrity of alpha-mangostin and related xanthones by avoiding excessive heat or harsh solvents. The result is a thoroughly researched ingredient optimized for performance, supported by Zubb Biotech’s ongoing R&D and technical support capabilities. Alpha-Pure XANTHONE embodies both traditional botanical power and modern scientific precision, giving manufacturers a competitive edge in their formulations.
One Ingredient, Many Possibilities: From Creams to Capsules
Alpha-Pure XANTHONE is highly versatile across different product applications:
- Dietary Supplements: This nutraceutical-grade extract can be used in capsules, tablets, or powdered drink mixes. Its fine powder blends well with vitamins and herbs in antioxidant complexes or anti-aging formulas. Supplement developers can leverage its benefits for immune support, anti-inflammatory relief, or general wellness products. (For liquid products, using Zubb’s nano-emulsion technology or other solubilizers is recommended to ensure uniform dispersion.)
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Skincare and Cosmetics: Alpha-Pure XANTHONE is ideal for premium skincare formulations. It can be incorporated into serums, creams, lotions, and masks to provide anti-aging, anti-acne, and brightening effects. For example, in an anti-aging cream it helps protect collagen in the skin; in an acne gel or toner it reduces bacteria and inflammation; in a brightening serum it contributes to a more radiant complexion. Its stability and efficacy make it suitable for “cosmeceutical” products where scientific validation is a key selling point.
Zubb Biotech provides guidance on optimal usage levels and formulation techniques so that clients can maximize the performance of Alpha-Pure XANTHONE in any format.
Clean Beauty Certified: Trusted by Formulators, Loved by Consumers
Quality and safety are paramount for Alpha-Pure XANTHONE. The ingredient is derived solely from mangosteen fruit peel and produced under strict GMP conditions, yielding a clean, contaminant-free profile. It is 100% natural in origin with no synthetic additives. Moreover, the extract contains no silicones, oils, artificial fragrances, parabens, or alcohol, making it ideal for clean beauty and health products. Alpha-Pure XANTHONE is also guaranteed cruelty-free – no animal testing is involved at any stage of its development.
Every batch undergoes stringent testing to ensure it meets the highest quality and safety standards. Zubb Biotech’s internal labs and partner institutions verify the extract’s purity, potency, and microbiological safety. Comprehensive documentation (COA, MSDS, etc.) is available with each shipment, and certifications such as Halal or relevant regulatory approvals can be provided if required. These measures reflect Zubb Biotech’s commitment to delivering a safe, reliable ingredient that manufacturers can trust.
Make It Happen: Your Next Hero Ingredient Starts Here
Elevate your product line with the proven power of Alpha-Pure XANTHONE. Whether you are developing the next best-selling supplement or a breakthrough skincare line, Zubb Biotech is ready to be your innovation partner. We invite OEM manufacturers and brand owners to contact us and experience the Zubb Biotech difference. With our deep industry expertise and science-backed ingredients, we help you create products that stand out.
By choosing Alpha-Pure XANTHONE, you gain not only a premium ingredient but also a dedicated team offering formulation support and regulatory guidance. We accommodate both small pilot projects and large-scale production needs with equal commitment. Contact Zubb Biotech today to request samples or consult with our specialists about integrating Alpha-Pure XANTHONE into your product line. Let’s collaborate to bring the next generation of health and beauty products to market together.
Reference (References)
- Medicinal properties of mangosteen (Garcinia mangostana). Food Chem. Toxicol. 46(10):3227–3239 (2008). DOI: https://doi.org/10.1016/j.fct.2008.07.024
- Widowati W. et al. Anti-aging Effects of Mangosteen Peel Extract and Its Phytochemical Compounds: Antioxidant Activity, Enzyme Inhibition and Molecular Docking Simulation. Trop. Life Sci. Res. 31(3):127–144 (2020). DOI: https://doi.org/10.21315/tlsr2020.31.3.9
- Abate M. et al. Mangostanin, a Xanthone Derived from Garcinia mangostana Fruit, Exerts Protective and Reparative Effects on Oxidative Damage in Human Keratinocytes. Pharmaceuticals 15(1):84 (2022). DOI: https://doi.org/10.3390/ph15010084
- Yuvanatemiya V. et al. A Review of the Influence of Various Extraction Techniques and the Biological Effects of the Xanthones from Mangosteen (Garcinia mangostana L.) Pericarps. Molecules 27(24):8775 (2022). DOI: https://doi.org/10.3390/molecules27248775
- Alam M.K. et al. The Potential of α-Mangostin from Garcinia mangostana as an Effective Antimicrobial Agent—A Systematic Review and Meta-Analysis. Antibiotics 11(6):717 (2022). DOI: https://doi.org/10.3390/antibiotics11060717
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