ALPHA-PURE XANTHONE
Purified xanthone extract derived from Garcinia mangostana (mangosteen) peel exhibits broad-spectrum antimicrobial activity. Rich in potent antioxidants, the extract suppresses collagenase activity and inhibits bacterial proliferation, leading to a gentle reduction of cutaneous inflammation. These combined mechanisms help diminish acne lesions and fine wrinkles while restoring a naturally brighter, more radiant complexion.
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Alpha-Pure XANTHONE – a highly purified xanthone isolated from the “Queen of Fruits,” driving the next generation of health-and-beauty formulations.
Alpha-Pure XANTHONE is a high-purity xanthone extract derived from mangosteen (Garcinia mangostana) peel. Enriched with potent antioxidant, anti-aging, and antimicrobial activities, it is tailored for use in premium nutraceutical and cosmetic formulations.
Heritage of Mangosteen Peel: From Traditional Herbal Legend to a World-Class Bioactive Extract
Thai people have celebrated the mangosteen—the “Queen of Fruits”—since the Ayutthaya era. While its deep-purple flesh is prized for flavour, the peel has long been recognised for its medicinal value; traditional Thai medical texts document its astringent, anti-inflammatory, and antimicrobial properties. For centuries, villagers have decocted mangosteen peel to cleanse wounds or ground it into a powder to suppress odours and aid healing.
However, in-depth scientific investigations have revealed that the peel’s wound-healing power originates from the xanthone family of compounds, with α-mangostin as the principal actor. This molecule has been cited in over 300 international journal publications for its pronounced antioxidant, anti-inflammatory, and acne-causing antibacterial activities.
Accordingly, Zubb Biotech has fused local ethnobotanical wisdom with advanced biotechnology to create Alpha-Pure XANTHONE at a purity of ≥ 95 % w/w. This high-grade refinement minimizes batch-to-batch variability and maximizes bio-efficacy, ensuring that manufacturers worldwide can trust this authentic Thai ingredient to meet rigorous international quality standards.
Purified Xanthone Power: Unified Acne Control, Anti-Aging, and Anti-Inflammatory Action
Alpha-Pure XANTHONE is a purified xanthone extract from mangosteen peel, rigorously standardised to a high concentration of key constituents—especially α-mangostin—without added fillers or unnecessary impurities. The product is supplied as a fine, pale-yellow powder that blends easily into both dietary-supplement and cosmetic formulations. Typical Mangosteen Powder Deep-level purification delivers a much higher active content per gram allowing smaller inclusion levels while still producing clear, potent effects. It is derived from 100 % natural raw material with no synthetic processing Alpha-Pure XANTHONE fully meets clean-label requirements yet remains densely packed with scientifically validated bioactives.Every production batch undergoes strict quality control: Zubb Biotech ensures that each lot passes safety, purity, and active-strength testing before shipment. Product developers can therefore rely on a consistent, dependable active for their own formulas. In short, Alpha-Pure XANTHONE is an effective way to add the proven “health and beauty” benefits of mangosteen to premium products, backed throughout by Zubb Biotech’s expertise and credibility.
Alpha-Pure XANTHONE: an antioxidant powerhouse for cellular health and aesthetic vitality
Alpha-Pure XANTHONE offers a broad spectrum of scientifically validated benefits, making it ideal for both nutraceuticals and advanced skin-care formulations:
- Powerful Antioxidant Activity
Mangosteen-derived xanthones effectively scavenge reactive oxygen species, protecting cellular components and slowing intrinsic ageing processes. Multiple studies show that these antioxidants mitigate cellular degeneration and reduce the risk of age-related chronic disorders at the molecular level. Incorporating Alpha-Pure XANTHONE into a formulation helps preserve skin youthfulness and supports overall health by interrupting free-radical-induced damage.
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Anti-inflammatory Action
The bioactive constituents of this extract exert pronounced anti-inflammatory effects, soothing irritated skin and helping the body regulate inflammatory responses more effectively. These properties make Alpha-Pure XANTHONE especially valuable for formulations that aim to reduce redness, swelling, or cutaneous discomfort, as well as for nutraceuticals designed to support joint health or modulate systemic inflammation.
- Anti-aging and Skin Rejuvenation
Alpha-Pure XANTHONE supports skin protection and recovery through multiple mechanisms. Research has shown that mangosteen-peel extract inhibits collagenase and elastase—enzymes responsible for degrading dermal collagen and elastin—as well as Tyrosinase inhibitor, which breaks down hyaluronic acid. By safeguarding the skin’s structural proteins and moisture matrix, the extract helps maintain firmness, elasticity, and hydration.
- Antimicrobial / Anti-acne Efficacy
Mangosteen-derived xanthones possess intrinsic antimicrobial properties, with marked potency against acne-causing bacteria. Alpha-Pure XANTHONE concentrates this activity so effectively that only minimal inclusion levels are required. In vitro studies show that α-mangostin inhibits the growth of Propionibacterium acnes (now Cutibacterium acnes) and Staphylococcus epidermidis at remarkably low concentrations, confirming its strong potential for controlling acne breakouts.
Clinical trials in human volunteers demonstrated that a mangosteen-peel gel reduced acne lesions by almost 47 % within 28 days compared with placebo, with most participants reporting high satisfaction with the outcome. This combined antimicrobial and anti-inflammatory efficacy positions Alpha-Pure XANTHONE as an outstanding key ingredient for anti-acne skin-care formulas, antiseptic cosmeceuticals, and natural wound-healing products.
All of the benefits described above are supported by peer-reviewed scientific studies and well-documented traditional use, underscoring the value of Alpha-Pure XANTHONE as a truly multifunctional bioactive. Product developers can readily integrate this extract to enhance both the efficacy and market appeal of their formulations.Marketing claims—such as potent antioxidant activity, anti-aging efficacy, and enhanced skin health—can be made with full confidence, as they are firmly supported by clear, peer-reviewed scientific evidence.
Advanced Extraction Technology: Unlocking the Full Bioactive Power of Xanthones
Alpha-Pure XANTHONE is the product of Zubb Biotech’s cutting-edge innovations in natural-compound extraction and purification. By applying advanced techniques, the research team isolates xanthones from mangosteen peel at exceptionally high purity, ensuring that every dose delivers a concentrated, fully potent active profile. This process—developed and continuously refined in collaboration with leading institutions such as Kasetsart University—yields a highly efficacious yet inherently safe natural ingredient.
Unlike conventional herbal powders or crude extracts that often show wide variability in bioactive content, Alpha-Pure XANTHONE undergoes rigorous removal of non-beneficial impurities while selectively enriching the molecular species with proven physiological value. The proprietary extraction technology also preserves the integrity of α-mangostin and other xanthones by avoiding excessive heat and harsh chemicals, maintaining both structural fidelity and biological activity.
The result is a meticulously researched and optimized bioactive ingredient backed by comprehensive technical data and expert support from Zubb Biotech. By uniting traditional botanical power with modern scientific precision, Alpha-Pure XANTHONE provides manufacturers with a distinct competitive edge for premium product formulations.
One‐stop beauty solution—versatile for both skin-care and color-cosmetic formulations.
Alpha-Pure XANTHONE can be incorporated into a wide array of product categories throughout the health-and-beauty sector:
- Skin-care cosmetics: Alpha-Pure XANTHONE is ideally suited as an active ingredient in premium formulations. It can be incorporated into serums, creams, lotions, and facial masks to deliver anti-aging, anti-acne, and brightening benefits. For example, in an anti-wrinkle cream it helps protect dermal collagen; in an acne gel or toner it suppresses bacterial growth and inflammation; and in a brightening serum it promotes a more even, radiant complexion. The extract remains chemically stable and fully bioactive across diverse formulation matrices, making it a compelling science-backed efficacy driver for cosmetic lines that require research-validated actives.
Furthermore, Zubb Biotech’s team of specialists is on hand to advise on the optimal use of Alpha-Pure XANTHONE—from recommended inclusion levels to blending techniques—so that clients can realise its full efficacy in their finished products.
Clean, Safe, and Certified: Standards You Can Trust in Every Formulation
Zubb Biotech places the highest priority on safety and quality at every step of the Alpha-Pure XANTHONE process. The ingredient is extracted from mangosteen peel under GMP-compliant conditions, yielding a clean, contaminant-free, 100 % natural extract with no synthetic additives. It is completely free of silicones, oils, alcohol, fragrances, and parabens, making it perfectly suited to clean-beauty and other gentle formulations that consumers increasingly demand. Importantly, Alpha-Pure XANTHONE is never tested on animals at any stage of research or production.
Each production batch of Alpha-Pure XANTHONE undergoes stringent, internationally benchmarked quality-and-safety testing—including heavy-metal screening, microbial contamination assays, and active-compound quantification—to guarantee that customers receive material of the highest caliber. Zubb Biotech also collaborates continuously with academic experts to advance product research and development, ensuring that the scientific data underpinning this ingredient remain current and reliable.
For commercial release, we supply comprehensive documentation such as a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and any additional certifications required by clients. These documents affirm Zubb Biotech’s commitment to delivering safe, premium-quality raw materials that formulators can incorporate into consumer products with complete confidence.
It’s time to elevate your current formulation—partner with us to make it truly stand out.
Boost your product potential with the power of Alpha-Pure XANTHONE. Whether you are formulating a cutting-edge dietary supplement or developing an innovative skin-care cosmetic, Zubb Biotech stands ready to be your trusted innovation partner. We welcome ODM/OEM supplement manufacturers, cosmetic brand owners, and health-product developers to discover the unique advantages we provide. Backed by our expertise in scientifically validated raw materials and actives, we help you craft distinctive, competitive products that excel in today’s marketplace.
Selecting Alpha-Pure XANTHONE is more than a raw-material purchase; it grants you full support from our professional team, ready to provide comprehensive guidance on formulation development and regulatory compliance. We accommodate flexible order sizes—from small trial batches to large-scale commercial quantities—delivered with attentive service. Contact Zubb Biotech today for further information or to request a sample of Alpha-Pure XANTHONE. Our specialists are eager to help you integrate this high-value bioactive into your next generation of products. Partner with us and advance together toward success in the health-and-beauty industry.
| Information | Detail |
|---|---|
| Trade Name | Alpha-Pure XANTHONE |
| Origin | Mangosteen pericarp, Thailand |
| Scientific Name | Garcinia mangostana L. |
| INCI Name | Garcinia Mangostana Peel Extract |
| Grade | Cosmetic / Food-grade |
| Key Actives |
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| Effective Dose | Cosmetic 0.015% w/w |
| Other information | – |
References
- Medicinal properties of mangosteen (Garcinia mangostana). Food Chem. Toxicol. 46(10):3227–3239 (2008). DOI: https://doi.org/10.1016/j.fct.2008.07.024
- Widowati W. et al. Anti-aging Effects of Mangosteen Peel Extract and Its Phytochemical Compounds: Antioxidant Activity, Enzyme Inhibition and Molecular Docking Simulation. Trop. Life Sci. Res. 31(3):127–144 (2020). DOI: https://doi.org/10.21315/tlsr2020.31.3.9
- Abate M. et al. Mangostanin, a Xanthone Derived from Garcinia mangostana Fruit, Exerts Protective and Reparative Effects on Oxidative Damage in Human Keratinocytes. Pharmaceuticals 15(1):84 (2022). DOI: https://doi.org/10.3390/ph15010084
- Yuvanatemiya V. et al. A Review of the Influence of Various Extraction Techniques and the Biological Effects of the Xanthones from Mangosteen (Garcinia mangostana L.) Pericarps. Molecules 27(24):8775 (2022). DOI: https://doi.org/10.3390/molecules27248775
- Alam M.K. et al. The Potential of α-Mangostin from Garcinia mangostana as an Effective Antimicrobial Agent—A Systematic Review and Meta-Analysis. Antibiotics 11(6):717 (2022). DOI: https://doi.org/10.3390/antibiotics11060717
